>In 1986, a meeting at the Institute Of Medicine defined gene therapy as the addition or replacement of a gene in a targeted cell type. In the same year, the FDA announced that it had jurisdiction over approving "gene therapy" without defining the term. The FDA added a very broad definition in 1993 of any treatment that would ‘modify or manipulate the expression of genetic material or to alter the biological properties of living cells’. In 2018 this was narrowed to ‘products that mediate their effects by transcription or translation of transferred genetic material or by specifically altering host (human) genetic sequences’
mRNA vaccines don't alter the host genome, hence not gene therapy. You could use a broader definition I suppose since (ideally) they lead to the production of certain immune cells; and that would also include all other vaccines.
>In 1986, a meeting at the Institute Of Medicine defined gene therapy as the addition or replacement of a gene in a targeted cell type. In the same year, the FDA announced that it had jurisdiction over approving "gene therapy" without defining the term. The FDA added a very broad definition in 1993 of any treatment that would ‘modify or manipulate the expression of genetic material or to alter the biological properties of living cells’. In 2018 this was narrowed to ‘products that mediate their effects by transcription or translation of transferred genetic material or by specifically altering host (human) genetic sequences’
https://en.wikipedia.org/wiki/Gene_therapy#Classification
mRNA vaccines don't alter the host genome, hence not gene therapy. You could use a broader definition I suppose since (ideally) they lead to the production of certain immune cells; and that would also include all other vaccines.