This is fascinating, such that I went looking for more information on this phenomenon and found an interesting preprint regarding the polymorphism of ritonavir suggesting that specific milling processes are able to reliably produce each form.
At least I think that's what it says, I'm definitely not a chemist!
At least I think that's what it says, I'm definitely not a chemist!
https://chemrxiv.org/engage/chemrxiv/article-details/645112f...