> Each pixel must be labelled with metadata, such as illumination level, its 3D position, the scale, the sample type and how the sample was prepared.
Each pixel? Why? All of those except the 3D position apply to all the pixels in a given image, and the (2D) position of a pixel can be inferred from its location in the image.
Wait - are there optical microscopes that can create 3D images? I know you can see a 3D image if you peer into a binocular microscope, but AFAIK cameras for those things are always 2D cameras.
Each pixel? Why? All of those except the 3D position apply to all the pixels in a given image, and the (2D) position of a pixel can be inferred from its location in the image.
Wait - are there optical microscopes that can create 3D images? I know you can see a 3D image if you peer into a binocular microscope, but AFAIK cameras for those things are always 2D cameras.