For a very entertaining and educational book that tangentially related; I can highly recommend: Y - The Descent of Man by Steve Jones [0]
I am thrilled to see more chromosomes being mapped/sequenced. Please excuse my high-school level of biology knowledge here, but have we definitively progressed beyond correlation when it comes to genes, gene expression, and how they all interact?
Take "Blue eyes" as an example, we know that [1] OCA2 is responsible for brown/blue eye colour. BUT are we sure that none of the 20,000 others are involved/needed?
In laymans terms I would guess that to get 'blue eyes' would require several genes to ALL be on/active/present as well. More like a recipe, then a simple on/off it's located in 1 position.
I am thrilled to see more chromosomes being mapped/sequenced. Please excuse my high-school level of biology knowledge here, but have we definitively progressed beyond correlation when it comes to genes, gene expression, and how they all interact?
Take "Blue eyes" as an example, we know that [1] OCA2 is responsible for brown/blue eye colour. BUT are we sure that none of the 20,000 others are involved/needed?
In laymans terms I would guess that to get 'blue eyes' would require several genes to ALL be on/active/present as well. More like a recipe, then a simple on/off it's located in 1 position.
[0] https://www.goodreads.com/work/editions/436071-y-the-descent... [1] https://www.nature.com/articles/s41433-021-01749-x