Definitely not. This is intended for those "gaming" PC mice with extra buttons. I tried it with mine (I normally use a magic trackpad but sometimes, rarely, I need a real mouse) and it works really nice. The only thing I'm missing is horizontal scrolling but I have no idea how to fit it in there.
edit: it can scroll horizontally if you hold shift while scrolling
edit: it can scroll horizontally if you hold shift while scrolling