Controversial, but I think that rather than trying to make Web stuff (e.g. React) work in Python, a more fruitful direction would be to make ML stuff (e.g. PyTorch, OpenCV) work in Typescript.
Javascript/Typescript is way faster than Python, is ubiquitous and can run pretty much everywhere, has many engine implementations, has an incredibly wide ecosystem, has a type system (Typescript) that blows any Python type system out of the water, runs in browsers, has non-stupid package management systems (PIP is a joke), is easy to get started, etc.
<The world if data scientists/ML/CV people used Typescript.JPEG>
Javascript/Typescript is way faster than Python, is ubiquitous and can run pretty much everywhere, has many engine implementations, has an incredibly wide ecosystem, has a type system (Typescript) that blows any Python type system out of the water, runs in browsers, has non-stupid package management systems (PIP is a joke), is easy to get started, etc.
<The world if data scientists/ML/CV people used Typescript.JPEG>