Same situation for antibiotics. Fleming, in the actual Nobel prize acceptance speech, warned:
"It is not difficult to make microbes resistant to penicillin in the
laboratory by exposing them to concentrations not sufficient to kill them,
and the same thing has occasionally happened in the body."
<https://www.nobelprize.org/prizes/medicine/1945/fleming/lect...>
And so today we have infections resistant to practically every known antibiotic. And it's getting worse.
"It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body." <https://www.nobelprize.org/prizes/medicine/1945/fleming/lect...>
And so today we have infections resistant to practically every known antibiotic. And it's getting worse.