I've been running Cloudflare's implementation of HTTP3/QUIC called Quiche[1] on my server's NGINX for over a year. It powers several websites and has served hundreds of millions of responses. It was a little weird to set up, but I've not encountered any issues with it so far.
It will be interesting to see how their native implementation compares.
It will be interesting to see how their native implementation compares.
[1] https://github.com/cloudflare/quiche/tree/master/nginx