The Real Time Strategy (RTS) genre more or less died in the mid 2000s with Age of Empires II, Warcraft 3, and Starcraft being the ones that left a mark.
Since that time: Warcraft 3 died; Starcraft was supplanted by Starcraft 2 and both eventually died outside of the lucrative Korean pro scene. Age of Empires II also died until it saw a resurrection in the pro scene in the early 2010s which has lasted to today.
The RTS genre itself is still very much dead, seeing no new games worthy of note to this day.
Since that time: Warcraft 3 died; Starcraft was supplanted by Starcraft 2 and both eventually died outside of the lucrative Korean pro scene. Age of Empires II also died until it saw a resurrection in the pro scene in the early 2010s which has lasted to today.
The RTS genre itself is still very much dead, seeing no new games worthy of note to this day.