You can complain about ethics on this one but, for awhile, I was using an AHK script to autoclick through an aggressive "Your trial is over, Buy now please!" style dialog that randomized the position of the exit button for the box. The software would let you continue using it if you clicked through though.
Every ~200ms the script scanned a small portion of the screen where the exit button might appear in and if the script found the button then it would close the dialogue box for me.
Every ~200ms the script scanned a small portion of the screen where the exit button might appear in and if the script found the button then it would close the dialogue box for me.