Comment by hack_edu

With Prozac being one of the more mild antidepressants, one must imagine the results from even more refined drugs produced in recent decades. I also wonder how the mood stabilizers with antidepressant effects would intersect here.

But, remember that anxiety is one of the most common side effects of Prozac and similar drugs. Perhaps for every patient positively affected you have another who's anxiety is actually amplified.

Edit: Why downvote? This is both factual and informed by my anecdotal experience...