After decades of research focused on the amyloid cascade hypothesis, which claims that sticky plaques of amyloid-beta proteins between neurons are the main cause of Alzheimer's disease, many scientists are now turning their attention to deeper dysfunctions happening within cells. Some believe that the disease is caused by a variety of proteins that may be causing multiple cell dysfunctions, while others are focusing on the role of tau protein tangles, which also form inside neurons.
After decades of research focused on the amyloid cascade hypothesis, which claims that sticky plaques of amyloid-beta proteins between neurons are the main cause of Alzheimer's disease, many scientists are now turning their attention to deeper dysfunctions happening within cells. Some believe that the disease is caused by a variety of proteins that may be causing multiple cell dysfunctions, while others are focusing on the role of tau protein tangles, which also form inside neurons.