I think I landed in a place where it's basically "the compiler has insufficient information to achieve ideal optimization because some things can only be known at runtime."
Which is not exclusively an argument for runtime JIT— it can also be an argument for instrumenting your runtime environment, and feeding that profiling data back to the compiler to help it make smarter decisions the next time. But that's definitely a more involved process than just baking it into the same JavaScript interpreter used by everyone— likely well worth it in the case of things like game engines, though.
Which is not exclusively an argument for runtime JIT— it can also be an argument for instrumenting your runtime environment, and feeding that profiling data back to the compiler to help it make smarter decisions the next time. But that's definitely a more involved process than just baking it into the same JavaScript interpreter used by everyone— likely well worth it in the case of things like game engines, though.