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Comment by tait

The number of circulating CD34+ cells varies by individual, and by age.

I volunteered for an unstimulated collection when we were validating the process of stem cell collection at my work. I was at the upper limit of normal, but I technically had enough in CD34+ cells in my circulation to do a transplant even without stimulation, and I was in my early 30s at the time.

A single CD34+ cell can probably make a lot of RBCs. (Ok, to be pedantic, I'm not 100 percent sure they are really CD34+ cells, I was taught that CD34+ is a marker for myeloblasts, and the cell population you would probably want are the CD34- hematogones as they are self-replenishing. The article didn't seem to say either way).

parent tait 4 years ago

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