Comment by mjard

Thanks for the information! My Motu (M2) does live on a linux machine and it's been relatively painless, worked on MacOs as well, but required a driver download on Windows. I never dug into why. Audio interfaces tend to be finicky things on their own, I also have an Arturia Audio Fuse Studio that needs to be "rebooted" from time to time, no matter what OS its connected to.