It does! Generally if you quit you can't collect unemployment insurance, but if your boss places unreasonable expectations on you or creates a hostile work environment you can argue it was constructive dismissal and collect unemployment even if you quit. The current Twitter situation is ripe for such claims.
Criteria from Wikipedia: "The Equal Employment Opportunity Commission has provided a 3-part test to determine whether or not a constructive discharge has occurred: (1) a reasonable person in the complainant's position would have found the working conditions intolerable; (2) conduct that constituted discrimination against the complainant created the intolerable working conditions; and (3) the complainant's involuntary resignation resulted from the intolerable working conditions"
Criteria from Wikipedia: "The Equal Employment Opportunity Commission has provided a 3-part test to determine whether or not a constructive discharge has occurred: (1) a reasonable person in the complainant's position would have found the working conditions intolerable; (2) conduct that constituted discrimination against the complainant created the intolerable working conditions; and (3) the complainant's involuntary resignation resulted from the intolerable working conditions"