They did adjust for confounders available in the Framington heart study.
Observational studies are less good at showing causation, sure.
Whilst I can't see the original article, the news summary insinuated a dose related effect. A sample size of >2000 is also decent.
Naturally in an ideal world you'd want a 3 arm, 20 year long, randomised placebo controlled double blinded study. But who would ever 1. Pay for it, 2. Wait that long.
Observational studies are less good at showing causation, sure.
Whilst I can't see the original article, the news summary insinuated a dose related effect. A sample size of >2000 is also decent.
Naturally in an ideal world you'd want a 3 arm, 20 year long, randomised placebo controlled double blinded study. But who would ever 1. Pay for it, 2. Wait that long.