Sure. But what is known about atherosclerosis is that plaques are not _on_ the arterial wall, but _inside_ the arterial wall. For plagues to form, fats have to be pulled into the arterial wall. How does this happen? Inflammation as designed opens up the arterial wall as a way to allow immune cells passage. Atherosclerosis happens when you have a bunch of fat in your arteries and you open them up to go inside. That's why cheeseburgers and pizza are the perfect heart disease vectors (Western diet). The bread parts cause inflammation via innate immunity (saccharomyces receptors) and the saturated fat parts (cheese and meat) flow in.
https://pubmed.ncbi.nlm.nih.gov/18163971/