Comment by guardiangod

Yup I ran out of PCIe slots in my last computer-

1x Bluetooth+Wifi adapter (offload the USB bus)

1x Highpoint USB 3 controller (the only USB3 controller that is reliable for work)

1x Quad network ports adapter

1x Video card

Things I wanted to install but couldn't-

1x M.2 nvme adapter card

1x Video card