Scott McCloud of Zot fame was an early adopter of the web, I attended a talk from him where he was talking about how frustrated he was that the 3 panel format had persisted to the web, when there were so many ways to use space creatively.
He later adapted that talk for his "understanding comics" Ted talk. Worth a watch if you love the medium
He later adapted that talk for his "understanding comics" Ted talk. Worth a watch if you love the medium