Not sure if you should be reminded of how alpha fold started, it started by winning a competition thought un winnable by academics. Top labs working in protein structure prediction have fundamentally changed direction after alpha fold and are working to do the same even better.
This is not the first (or even tenth) time I’m seeing an academic trying to undermine genuine progress almost to the level of gaslighting. Comparing alphafold to conventional homology modeling is disingenuous at its most charitable interpretation.
Not sure what else to say. Structural biology has always been the weirdest field I’ve seen, the way students are abused (crystallize and publish in nature or go bust), and how every nature issue will have three structure papers as if that cures cancer every day. I suppose it warps one’s perception of outsiders after being in such a bubble?
signed, someone with a PhD in biomedical engineering, did a ton of bio work.
This is not the first (or even tenth) time I’m seeing an academic trying to undermine genuine progress almost to the level of gaslighting. Comparing alphafold to conventional homology modeling is disingenuous at its most charitable interpretation.
Not sure what else to say. Structural biology has always been the weirdest field I’ve seen, the way students are abused (crystallize and publish in nature or go bust), and how every nature issue will have three structure papers as if that cures cancer every day. I suppose it warps one’s perception of outsiders after being in such a bubble?
signed, someone with a PhD in biomedical engineering, did a ton of bio work.