Comment by wtetzner

> (some) reasons behind the longevity of many of those centenarians have been identified: low mTOR activity and high omega 3 intake.

I wonder how true this is, given that carbs trigger mTOR harder and longer than protein, and the Mediterranean diet seems pretty high-carb.

In any case, if you're worried about mTOR, intermittent fasting is probably the simplest life-style change you can make.