Noise is used today in several high-profile projects:
WhatsApp uses the "Noise Pipes" construction from the specification to perform encryption of client-server communications
WireGuard, a modern VPN, uses the Noise IK pattern to establish encrypted channels between clients
Slack's Nebula project, an overlay networking tool, uses Noise
The Lightning Network uses Noise
I2P uses Noise
https://duo.com/labs/tech-notes/noise-protocol-framework-int...