I think the best-case scenario is that 'we' become something different than we are right now. The natural tendency of life(on the local scale) is toward greater information density. Chemical reactions beget self-replicating molecules beget simple organisms beget complex organisims beget social groups beget tribes beget city states beget nations beget world communities. Each once of these transitions looks like the death of the previous thing and in actuality the previous thing is still there, just as part of a new whole. I suspect we will start with natural people and transition to some combination of people whose consciousness exists, at least partially, outside of the boundaries of their skulls, people who are mostly information on computing substrate outside of a human body, and 'people' who no longer have much connection with the original term.
And that's OK. We are one step toward the universe understanding itself, but we certainly aren't the final step.
And that's OK. We are one step toward the universe understanding itself, but we certainly aren't the final step.