Comment by saidajigumi

As a software rather than keyboard hack, I've been using and loving the following setup on macOS: * Remap Caps Lock to Ctrl * Then use Hammerspoon[1] to map Ctrl(hold) / Esc (momentary press)

This essentially puts both Ctrl and Esc in a comfortable position on the home row, probably my favorite "ergo hack" ever.

[1] http://www.hammerspoon.org/