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Comment by PragmaticPulp

> Considering how often antidepressants tend to be a hit-or-miss game (not to speak of side effects), I am a bit annoyed psychedelics don't get more attention for medical use.

Psychedelics are actually extremely hit-or-miss as well. Anecdotally, psychedelics don't always send someone in the right direction post-trip. If you scroll the comments in any popular psychedelics-for-depression post on Reddit, there are almost as many negative experience reports (including some long-lasting) as there are positive reports. The positive reports receive the bulk of upvotes, though, so you have to scroll down to see them.

Perhaps less anecdotally, any medical professional will see a non-trivial number of people with significant negative effects of psychedelics, from worsening depression to HPPD to existential crises or psychoses. An actual doctor had a great comment on the previous discussion: https://news.ycombinator.com/item?id=30995831

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