My least favourite thing about GNOME is that it has co-opted GTK and sabotaged it so that even determined developers stand no chance of achieving native look and feel on other platforms and desktop environments. The G in GTK now (de facto, not de jure) stands for GNOME.
(Expressed otherwise: I kind of have to use parts of GNOME because it has infected GTK and it’s much more difficult to avoid GTK than to avoid the rest of GNOME.)
(Expressed otherwise: I kind of have to use parts of GNOME because it has infected GTK and it’s much more difficult to avoid GTK than to avoid the rest of GNOME.)