Comment by kevingadd

In practice it's not possible to optimize "generally" for all possible target architectures your wasm will run on. You're going to optimize for x86-64 or ARM, and probably going to specifically optimize for modern intel, modern amd, or apple's m1. If you try to optimize for everything you're going to run into really painful tradeoffs and probably have mediocre performance on a bunch of architectures after a lot of hard work.