I'm not aware of any evidence that activity at CBR1 or 2 has any effect on the proliferation of SARS-CoV-2
The study at hand doesn't suggest a mechanism and most endogenous transmitters are extremely local. This means that they won't necessarily go where the virus is. Taking an exogenous drug allows for a greater degree of tissue distribution
On top of all that, the study also mentions this:
>The CBD metabolite 7-OH-CBD, but not a panel of closely related CBD congeners, exhibits antiviral activity
This makes me suspect that the mechanism of action is unique to CBD and would likely not be the same as the endogenous transmitters
The study at hand doesn't suggest a mechanism and most endogenous transmitters are extremely local. This means that they won't necessarily go where the virus is. Taking an exogenous drug allows for a greater degree of tissue distribution
On top of all that, the study also mentions this:
>The CBD metabolite 7-OH-CBD, but not a panel of closely related CBD congeners, exhibits antiviral activity
This makes me suspect that the mechanism of action is unique to CBD and would likely not be the same as the endogenous transmitters