Whether or not the host knows where the prize is absolutely makes a difference. There's a reason why it's stated twice in TFA, very unambiguously, that the host is intentionally opening a door they know does not contain the prize.
In the case of a host that doesn't know where the prize is, your odds don't improve by switching. Think of it slightly differently: Imagine you pick a door, and then the host, who has no idea what's behind the doors, also picks one. Then the remaining door opens and reveals that there's nothing behind it. There's really no difference between your choice and the hosts.
In the case of a host that doesn't know where the prize is, your odds don't improve by switching. Think of it slightly differently: Imagine you pick a door, and then the host, who has no idea what's behind the doors, also picks one. Then the remaining door opens and reveals that there's nothing behind it. There's really no difference between your choice and the hosts.