All of the GoF research procedures I've read stress natural evolution, but still rely on random mutations at the end of the day, which would still leave you with a natural looking count of silent mutations in the general case.
As a GoF researcher you don't want to cull 'silent' mutations because those are a major source of building blocks for useful mutations.
As a GoF researcher you don't want to cull 'silent' mutations because those are a major source of building blocks for useful mutations.