It's worth clarifying: un-boosted vaccination or past infection seem to have greatly reduced ability to prevent infection with Omicron. There is still substantial (lessened, but not as drastically lessened) protection against serious illness / death.
My understanding is that protection-against-infection and protection-against-death rely on different aspects of the immune system. The primary protection against initial infection comes from antibodies, which are narrowly targeted. Other systems are more flexible, but don't kick in quickly enough to ward off a mild infection.
And the takeaway is still: get vaccinated, get boosted.
My understanding is that protection-against-infection and protection-against-death rely on different aspects of the immune system. The primary protection against initial infection comes from antibodies, which are narrowly targeted. Other systems are more flexible, but don't kick in quickly enough to ward off a mild infection.
And the takeaway is still: get vaccinated, get boosted.