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Comment by ashwal

There's many papers showing similar. (My personal favorite is https://www.science.org/doi/10.1126/scitranslmed.aaw8412 where they removed the claimed target for various cancer therapies and many still worked)

If you've ever been within a mile of a research lab this shouldn't be remotely shocking. Typical research is done rapidly, sloppily, and in a context where getting the "right" answer is the only incentive.

The replication crisis that hit psych is only being held back by (IMO) that bio is harder to replicate due to tooling, protocols, reagents, cell lines, etc.

In complex systems you have the degrees of freedom to be wrong at a scale that folks still do not appreciate.

parent ashwal 4 years ago

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