At the risk of being "that guy", it has to be said that this kind of study is unreliable. Posting a bunch of messages to r/drugs and r/psychedelics to come take their survey is going to suffer from all sorts of statistical biases.
It is still better than the lowest for the study, the sample size of one: "Well this is what I experienced". Yet here I go.
I have always been a materialist, and I've also never done drugs (I'm in my 50s). A few years back I bought some lysergamides and tryptamines online, and over the course of two years did between 20 and 30 experiments, though never of high doses (at most, 200 ug LSD). I found the LSD to be quite interesting, but not the least bit spiritual.
The first time I did 4-aco-dmt (aka psilacetin), a very close relative to psilocybin, was a different story. It was a 25mg-ish dose, taken orally. It was far more intense, and dreamy, and soporific than LSD (for me), and it gave me a glimpse of what something I was hoping to experience: spirituality. It was unfortunately fleeting -- I was lost in "the light" but then became aware that I was actually lying in a bed, and without thinking, opened my eyes for a moment to confirm. I closed my eyes but that moment in the light was gone for good.
I've tried a few more times, but it has mostly been uncomfortable and confusing way to spend a couple hours.
Anyway, I came away from those experiments even more of a materialist than I was before. If a hundred micrograms or a few milligrams of small molecule can so disrupt one's mind, if it can profoundly change your perceptions, if it can induce a feeling of being in a divine presence, it confirmed to me that the brain is all just chemistry.
It is still better than the lowest for the study, the sample size of one: "Well this is what I experienced". Yet here I go.
I have always been a materialist, and I've also never done drugs (I'm in my 50s). A few years back I bought some lysergamides and tryptamines online, and over the course of two years did between 20 and 30 experiments, though never of high doses (at most, 200 ug LSD). I found the LSD to be quite interesting, but not the least bit spiritual.
The first time I did 4-aco-dmt (aka psilacetin), a very close relative to psilocybin, was a different story. It was a 25mg-ish dose, taken orally. It was far more intense, and dreamy, and soporific than LSD (for me), and it gave me a glimpse of what something I was hoping to experience: spirituality. It was unfortunately fleeting -- I was lost in "the light" but then became aware that I was actually lying in a bed, and without thinking, opened my eyes for a moment to confirm. I closed my eyes but that moment in the light was gone for good.
I've tried a few more times, but it has mostly been uncomfortable and confusing way to spend a couple hours.
Anyway, I came away from those experiments even more of a materialist than I was before. If a hundred micrograms or a few milligrams of small molecule can so disrupt one's mind, if it can profoundly change your perceptions, if it can induce a feeling of being in a divine presence, it confirmed to me that the brain is all just chemistry.