The only justified situation I can find is when you are working on two (or more) independent components at the same time.
My pain point in particular with PYTHONPATH (or playing with sys.path) is that people tend to use it with the only purpose of making import lines shorter, which brings naming collisions of all sorts when you aren't creative enough.
My pain point in particular with PYTHONPATH (or playing with sys.path) is that people tend to use it with the only purpose of making import lines shorter, which brings naming collisions of all sorts when you aren't creative enough.