I recently switched from an iPhone to a Pixel with GrapheneOS and it's been great so far (a couple months now or so).
It's extremely usable, with only minor hiccups if you're trying to use any apps that require Google Play Services. GrapheneOS does allow you to install play services sandboxed without any special system access (just like any other app). I've replaced a couple of apps that required those to FOSS alternatives without much hassle at all.
Install via WebUSB[0] was very simple and went without a hitch, and at the end of the day is basically just a normal Android experience, just much more secure and private by default.
It's extremely usable, with only minor hiccups if you're trying to use any apps that require Google Play Services. GrapheneOS does allow you to install play services sandboxed without any special system access (just like any other app). I've replaced a couple of apps that required those to FOSS alternatives without much hassle at all.
Install via WebUSB[0] was very simple and went without a hitch, and at the end of the day is basically just a normal Android experience, just much more secure and private by default.
0: https://grapheneos.org/install/web