Comment by gjulianm

I do care about the CPython GIL. I develop a program with a lot of analysis and output to custom formats. The things that can go to the underlying C extension go there, but the development cost is far higher for migrating stuff there. I'd like to be able to parallelize the different sections, but multiprocessing is a mess (only pickable data can be used, no shared state), threading doesn't give me any benefit due to the GIL, and PyPy hasn't worked the last three times I tried. Also, improvements can stack. If I get threading working, I can still move more things to the C extension to improve performance, or migrate finally to PyPy (if they manage to remove the GIL).