Comment by koeng

Here is the paper link - https://doi.org/10.1016/j.molcel.2021.08.008

They did a lot of hard work to get there! A few years we synthesized some prokaryotic argonaute proteins for their lab. Bet they were considering them as an alternative to CRISPR proteins. Excited to use CasMINI in some bacterial systems, Cas9/Cpf1 are kinda annoying to synthesize.