The most baffling thing is not standardising CT values for RT-PCR tests.
I have looked and I cannot even find how increasing CT values affect the false positive rate for the PCR testing. If my understanding is correct a single increment of CT essentially doubles the sensitivity of the test, so difference between CT value of 35 and 40 is 32 fold.
CDC is suggesting CT value of 28 for detecting breakthrough infections after vaccinations. And if I am not mistaken, a lot of places was using 35 for the CT value in RT-PCT tests.
So that means, a breakthrough infection needs to have 128 times viral load in someone who has been vaccinated to be considered as positive, than it is required to have considered as positive in a non-vaccinated person.
I have looked and I cannot even find how increasing CT values affect the false positive rate for the PCR testing. If my understanding is correct a single increment of CT essentially doubles the sensitivity of the test, so difference between CT value of 35 and 40 is 32 fold.
CDC is suggesting CT value of 28 for detecting breakthrough infections after vaccinations. And if I am not mistaken, a lot of places was using 35 for the CT value in RT-PCT tests.
So that means, a breakthrough infection needs to have 128 times viral load in someone who has been vaccinated to be considered as positive, than it is required to have considered as positive in a non-vaccinated person.
That is quite ridiculous.