Quokka looks interesting. An extension is definitely a possibility and if so it would support DOM, Vue, NodeJS, Electron, etc — not just run things in a separate NodeJS instance.
The other route I am considering is integrating backend, hosting, and a market — so the site becomes a vertically integrated code creation place.
The other route I am considering is integrating backend, hosting, and a market — so the site becomes a vertically integrated code creation place.