I use Safari as my daily browser, with AdGuard as my adblocker. (It's the second result on the Mac App Store for "ad blocker"—the first after AdBlock Pro, which I won't use because it sells whitelist space, AIUI.)
I...don't see ads.
It's not as hyper-configurable as uMatrix, and there are certainly annoyances that don't get filtered out (first-party videos, "subscribe to our newsletter" overlays, etc), but it's got some decent user input, such that I could probably block more of those if I cared to spend some effort, and...well, I just don't see ads in my common usage.
I...don't see ads.
It's not as hyper-configurable as uMatrix, and there are certainly annoyances that don't get filtered out (first-party videos, "subscribe to our newsletter" overlays, etc), but it's got some decent user input, such that I could probably block more of those if I cared to spend some effort, and...well, I just don't see ads in my common usage.