I've not tried Nuitka yet, but I've done similar things with 2 other tools to package up a Qt-based GUI tool that has a Windows installer, Mac ".dmg" or a Linux package:
* FBS (FMan's Build System) - worked well for a while, but we couldn't upgrade Qt past a certain version and he version we used was only happy with Python 3.6.
* Beeware - our current solution. Very, very happy with this; works smoothly, lets us use the latest Python and Qt versions and lets us make professional-looking installers that we can distribute.
* FBS (FMan's Build System) - worked well for a while, but we couldn't upgrade Qt past a certain version and he version we used was only happy with Python 3.6.
* Beeware - our current solution. Very, very happy with this; works smoothly, lets us use the latest Python and Qt versions and lets us make professional-looking installers that we can distribute.