Do you use multiple email addresses to organize your mail?

I have a ProtonMail Visionary account and have access to a bunch of possible email accounts. I'm growing more leery of allowing gmail to search what I do through their service so I want to begin switching over to the other account. That said, I don't want one account which could eventually get overrun with spam. I'd like to keep a main address for Bills/Important stuff, maybe one for shopping, one for blogs, etc. Do you do anything like this? If so, any advice? Thanks!