Comment Comment by heavyset_go > One thing I noticed is that - it gives me incredible mental boost a day after taking it. It just makes me feel normal and that to me is a 'boost'.I've read that loperamide doesn't just quell bowel problems with opioid withdrawal, but that it lessens cognitive symptoms, as well.Sounds like there might be some active metabolites, or that peripheral opioid receptor activation can affect cognition. parent heavyset_go 5 years ago
I've read that loperamide doesn't just quell bowel problems with opioid withdrawal, but that it lessens cognitive symptoms, as well.
Sounds like there might be some active metabolites, or that peripheral opioid receptor activation can affect cognition.