Comment by throwaway17824

While lack of human connection can be one cause or contributing factor for depression in individual cases, and may make a lot of people "depressed" in the informal coloquial sense, the notion that major depressive disorder across the spectrum and across society is singularly caused by lack of human interaction (or singularly caused by anything at all) is not a notion evidenced by any literature on depression I'm aware of, and is not a notion espoused by any of mental health professionals I've encountered who routinely successfully treat people with depression.