Well, I think they're trying to stimulate mucosal immunity, rather than trigger MHC presentation. But yes, more research is needed to determine effectiveness.
"This highlights one important advantage of an intranasal
vaccine: a robust mucosal immune response should greatly reduce or prevent this
systemic response by abrogating initial infection."
"This highlights one important advantage of an intranasal vaccine: a robust mucosal immune response should greatly reduce or prevent this systemic response by abrogating initial infection."