Comment Comment by pen2l Pasting from linked twitter thread, while this is encouraging, some things are left to be desired:1) No data for the most vulnerable older (>55) population2) Second dose absolutely necessary3) Safety profile less than desirable4) Durability of neutralizing Ab not so encouraging (decline from day 43~57)5) Very low CD8 T-cell responsesNovavas phase I results (NVX-CoV2373), probably due to be out soon, will be interesting. parent pen2l 6 years ago
1) No data for the most vulnerable older (>55) population
2) Second dose absolutely necessary
3) Safety profile less than desirable
4) Durability of neutralizing Ab not so encouraging (decline from day 43~57)
5) Very low CD8 T-cell responses
Novavas phase I results (NVX-CoV2373), probably due to be out soon, will be interesting.