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Comment by bhickey

I think to authors are overly optimistic in our ability detecting highly dilute samples. Pooling studies in Dengue Fever using RT-PCR found sensitivity fell faster than could be explained by dilution effects alone. At 100:1 or 20:1 pooling the false negative rate will be unacceptable.

Edit: false positive -> false negative

parent bhickey 6 years ago

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