Comment by wireprotocol

I am confused about what you mean. First, the federal government clearly has authority over international commerce. Second, the price of drugs in legal markets would be much lower, which would likely reduce revenue for criminal gangs in foreign lands. Third, the U.S.-Mexico border is long and it's hard to enforce smuggling laws, anyway. And fourth, Americans are quite capable of producing drugs on their own, and even more so if they were legal.