I've been thinking about this too. In fact I've started hacking on an app to solve this for my group of friends. To me the two primary issues are:
1. Sub groups without losing the context of the full group. I want to focus on a set of people and chat with them while also aware of what other groups are around. I want to be able to bring people into these groups at will. This also adds a gamification aspect where you can adjust groups, i.e. randomly mix, mix people who haven't talked to each other yet etc.
2. Multi monitor. I want to see everyone and real estate is limited on a single screen. I should be able to add multiple windows or computers to my chat and have everyone spread across those windows. Only one window / computer will submit video and audio for me though.
1. Sub groups without losing the context of the full group. I want to focus on a set of people and chat with them while also aware of what other groups are around. I want to be able to bring people into these groups at will. This also adds a gamification aspect where you can adjust groups, i.e. randomly mix, mix people who haven't talked to each other yet etc.
2. Multi monitor. I want to see everyone and real estate is limited on a single screen. I should be able to add multiple windows or computers to my chat and have everyone spread across those windows. Only one window / computer will submit video and audio for me though.